Symptoms

Symptoms of Peripheral Vascular Disease

Peripheral vascular disease symptoms include changes in skin temperature, extremity color, non-healing wounds, numbness or burning in legs or toes. Many patients with peripheral vascular disease have pain in their legs when walking. If you have restricted mobility or severe pain, make an appointment with your physician for a thorough examination.

A blockage in an artery to the legs may cause the following symptoms:

  • Coolness of the legs
  • Impotence in men
  • Loss of hair on toes, feet and legs
  • Non-healing wound or gangrene
  • Pain in calves, thighs, and/or buttocks during walking and relieved with rest
  • Pain in the feet at rest with severe blockage
  • Skin discoloration
  • Thickening of toenails
  • Tingling, numbness in the legs

A sudden blockage in an artery to the legs may cause the following symptoms:

  • Coolness
  • No pulse
  • Numbness or tingling
  • Paleness or whiteness
  • Paralysis (cannot move)
  • Sudden onset of pain

Aneurysms in the leg may not produce any symptoms. However, if symptoms are present, they may include:

  • Blue toes
  • Pulsating feeling behind the knee

If you notice long-term changes, make an appointment with your physician for a thorough examination. If you are unsure or have concern about your symptoms, seek medical attention. As with any medical condition, it is better to be safe than sorry.

Six niche centers within the Bluhm Cardiovascular Institute offer patient focused, specialized care, making the Bluhm Cardiovascular Institute a leading destination for both initial diagnoses and second opinions. These niche programs include physicians, nurses and a range of multidisciplinary specialists working with patients to navigate the complex health care system, ensuring continuity of care and a seamless shift from inpatient to outpatient services and ultimately home.

Contact Us
To schedule an appointment or inquire about services at the Bluhm Cardiovascular Institute at Northwestern Memorial Hospital, please call 312.NM.HEART (664.3278).

Cardiovascular Clinical Trials
For information regarding cardiovascular clinical trials:

Referring Physicians
Open communication and cooperation with referring physicians is a critical component of achieving high-quality care and minimizing the challenges that come with treating cardiovascular conditions. For physician-to-physician consultation regarding the best patient care, please contact the Bluhm Cardiovascular Institute at 312.NM.HEART (664.3278).


Six niche centers within the Bluhm Cardiovascular Institute offer patient focused, specialized care, making the Bluhm Cardiovascular Institute a leading destination for both initial diagnoses and second opinions. These niche programs include physicians, nurses and a range of multidisciplinary specialists working with patients to navigate the complex health care system, ensuring continuity of care and a seamless shift from inpatient to outpatient services and ultimately home.

Contact Us
To schedule an appointment or inquire about services at the Bluhm Cardiovascular Institute at Northwestern Medicine Lake Forest Hospital, please call 847.53.HEART (534.3278).

Cardiovascular Clinical Trials
For information regarding cardiovascular clinical trials:


Six niche centers within the Bluhm Cardiovascular Institute offer patient focused, specialized care, making the Bluhm Cardiovascular Institute a leading destination for both initial diagnoses and second opinions. These niche programs include physicians, nurses and a range of multidisciplinary specialists working with patients to navigate the complex health care system, ensuring continuity of care and a seamless shift from inpatient to outpatient services and ultimately home.

Contact Us
To schedule an appointment or inquire about services at the Bluhm Cardiovascular Institute at Northwestern Medicine Central DuPage Hospital or Northwestern Medicine Delnor Hospital, please call 630.232.0280

Cardiovascular Clinical Trials
For information regarding cardiovascular clinical trials: