Lupus and Kidney Disease

Lupus and Kidney Disease

Lupus nephritis is one of the most serious complications of lupus. In lupus nephritis, the immune system attacks your kidneys, which can lead to permanent kidney damage if it is not treated. Up to 60% of people with lupus may develop kidney disease.1

Symptoms of lupus nephritis may include:

  • Foamy or bloody pee
  • Swelling in the legs, ankles or feet
  • High blood pressure
  • Fatigue

At our lupus nephritis clinic, kidney and lupus doctors work together to diagnose and treat kidney disease in people with lupus. Early detection and treatment can help protect your kidneys.

References

  1. Lupus Therapeutics. Lupus clinical research: A new wave of innovation. lupustherapeutics.org. November 6, 2025