Finding the right treatment can be challenging for people with trigeminal neuralgia. Certain prescription medications can help reduce the pain of trigeminal neuralgia and the rate of attacks. These include:

• Antiepileptic drugs (carbamazepine, oxcarbazepine, gabapentin, phenytoin)
• Migraine drugs (sumatriptan)
• Tricyclic antidepressants (amitriptyline, nortriptyline)
• Baclofen

When trigeminal neuralgia symptoms do not respond enough to traditional medical therapy, surgery may help.