Center for Aortic Care Publications

1: Yoshida S, Manerikar A, Zhu M, Mehta C. Successful surgical treatment of Stanford type A aortic dissection due to Salmonella aortitis. J Cardiothorac Surg. 2023;18(1):233. doi: 10.1186/s13019-023-02318-x.

2: Mehta CK, Chiu S, Hoel AW, Vassallo P, Whippo B, Andrei AC, Schmidt MJ, Pham DT, Johnston DR, Churyla A, Malaisrie SC. Implementation of a direct-to-operating room aortic emergency transfer program: Expedited management of type A aortic dissection. Am J Emerg Med. 2023;70:113-118. doi: 10.1016/j.ajem.2023.05.036.

3: Baman JR, Malaisrie SC. What is aortic dissection? JAMA. 2023;330(2):198. doi: 10.1001/jama.2023.5592.

4: Nightingale M, Scott MB, Sigaeva T, Guzzardi D, Garcia J, Malaisrie SC, McCarthy P, Markl M, Fedak PWM, Di Martino ES, Barker AJ. Magnetic resonance imaging-based hemodynamic wall shear stress alters aortic wall tissue biomechanics in bicuspid aortic valve patients [published online ahead of print, 2023]. J Thorac Cardiovasc Surg. 2023;S0022-5223(23)00019-3. doi: 10.1016/j.jtcvs.2022.12.021.

5: Weiss EK, Jarvis K, Maroun A, Malaisrie SC, Mehta CK, McCarthy PM, Bonow RO, Avery RJ, Allen BD, Carr JC, Rigsby CK, Markl M. Systolic reverse flow derived from 4D flow cardiovascular magnetic resonance in bicuspid aortic valve is associated with aortic dilation and aortic valve stenosis: a cross sectional study in 655 subjects. J Cardiovasc Magn Reson. 2023;25(1):3. doi: 10.1186/s12968-022-00906-9.

6: Liu SZ, Engel JS, Bisen JB, Kilinc O, Quinn S, Hoel AW, Mehta CK, Markl M, Allen BD. Entry tear hemodynamics using 4D flow MRI in a patient with acute type B aortic dissection. Radiol Case Rep. 2023;18(3):1037-1040. doi: 10.1016/j.radcr.2022.12.033.

7: Kilinc O, Chu S, Baraboo J, Weiss EK, Engel J, Maroun A, Giese D, Jin N, Chow K, Bi X, Davids R, Mehta C, Malaisrie SC, Hoel A, Carr J, Markl M, Allen BD. Hemodynamic Evaluation of Type B Aortic Dissection Using Compressed Sensing Accelerated 4D Flow MRI. J Magn Reson Imaging. 2023;57(6):1752-1763. doi: 10.1002/jmri.28432.

8: Engel JS, Bharadwaj S, Elbaz M, Markl M, Allen BD, Malaisrie SC. Four-dimensional magnetic resonance after ascending aorta replacement and aortic valve repair with HAART 300 internal annuloplasty ring. J Card Surg. 2022;37(11):3899-3903. doi: 10.1111/jocs.16950.

9: Crawford EE, McCarthy PM, Malaisrie SC, Mehta CK, Puthumana JJ, Robinson JD, Markl M, Bonow RO, Fedak PWM. The need for comprehensive multidisciplinary programs, complex interventions, and precision medicine for bicuspid aortic valve disease. Ann Cardiothorac Surg. 2022;11(4):369-379. doi: 10.21037/acs-2021-bav-207.

10: Chu S, Kilinc O, Pradella M, Weiss E, Baraboo J, Maroun A, Jarvis K, Mehta CK, Malaisrie SC, Hoel AW, Carr JC, Markl M, Allen BD. Baseline 4D flow-derived in vivo hemodynamic parameters stratify descending aortic dissection patients with enlarging aortas. Front Cardiovasc Med. 2022;9:905718. doi: 10.3389/fcvm.2022.905718.

11: Johnson EMI, Scott MB, Jarvis K, Allen B, Carr J, Malaisrie SC, McCarthy P, Mehta C, Fedak PWM, Barker AJ, Markl M. Global aortic pulse wave velocity is unchanged in bicuspid aortopathy with normal valve function but elevated in patients with aortic valve stenosis: insights from a 4D flow MRI study of 597 subjects. J Magn Reson Imaging. 2023;57(1):126-136. doi: 10.1002/jmri.28266.

12: Malaisrie SC, Kislitsina ON, Wilsbacher L, Mendelson M, Puthumana JJ, Vassallo P, Kruse J, Andrei AC, McCarthy PM. Valve-sparing versus valve-replacing aortic root replacement in patients with aortic root aneurysm. J Card Surg. 2022;37(7):1947-1956. doi: 10.1111/jocs.16473.

13: Myers PO, Dayan V, Szeto WY, Thourani VH, Malaisrie SC, Moon MR, Prager RL, Ono M, Okita Y, Freemantle N, Milojevic M. Joint surgical associations (EACTS, LACES, ASCVTS, AATS, and STS) position statement regarding the VARC-3 definitions for aortic valve clinical research. J Thorac Cardiovasc Surg. 2022 ;163(5):1792-1794. doi: 10.1016/j.jtcvs.2021.12.053.

14: Williams MR, Jilaihawi H, Makkar R, O'Neill WW, Guyton R, Malaisrie SC, Brown DL, Blanke P, Leipsic JA, Pibarot P, Hahn RT, Leon MB, Cohen DJ, Bax JJ, Kodali SK, Mack MJ, Lu M, Webb JG. The PARTNER 3 bicuspid registry for transcatheter aortic valve replacement in low-surgical-risk patients. JACC Cardiovasc Interv. 2022;15(5):523-532. doi: 10.1016/j.jcin.2022.01.279.

15: Pradella M, Mozer AB, Baraboo JJ, Narang A, Gong FF, Budd AN, Allen BD, Mehta C. Blood flow dynamics in a giant left atrial appendage aneurysm visualized by 4D-flow CMR. JACC Case Rep. 2021 Dec 15;3(18):1924-1929. doi: 10.1016/j.jaccas.2021.10.009.

16: Sawicki KT, Mehta CK, Silverberg RA. Five-chambered heart: palpitations and syncope due to a left atrial appendage aneurysm. Circ Cardiovasc Imaging. 2021;14(12):1147-1150. doi: 10.1161/CIRCIMAGING.121.013469.

17: Mehta CK, Son AY, Chia MC, Budd AN, Allen BD, Vassallo P, Hoel AW, Brady WJ, Nable JV. Management of acute aortic syndromes from initial presentation to definitive treatment. Am J Emerg Med. 2022;51:108-113. doi: 10.1016/j.ajem.2021.10.016.

18: Bonow RO. Resurgence of the Ross procedure. Ann Cardiothorac Surg. 2021 Jul;10(4):512-514. doi: 10.21037/acs-2020-rp-196.

19: Soulat G, Scott MB, Allen BD, Avery R, Bonow RO, Malaisrie SC, McCarthy P, Fedak PWM, Barker AJ, Markl M. Association of regional wall shear stress and progressive ascending aorta dilation in bicuspid aortic valve. JACC Cardiovasc Imaging. 2022;15(1):33-42. doi: 10.1016/j.jcmg.2021.06.020.

20: Zilber ZA, Boddu A, Malaisrie SC, Hoel AW, Mehta CK, Vassallo P, Burris NS, Roldán-Alzate A, Collins JD, François CJ, Allen BD. Noninvasive morphologic and hemodynamic evaluation of type B aortic dissection: state of the art and future perspectives. Radiol Cardiothorac Imaging. 2021;3(3):e200456. doi: 10.1148/ryct.2021200456.

21: Malaisrie SC, Szeto WY, Halas M, Girardi LN, Coselli JS, Sundt TM 3rd, Chen EP, Fischbein MP, Gleason TG, Okita Y, Ouzounian M, Patel HJ, Roselli EE, Shrestha ML, Svensson LG, Moon MR; AATS Clinical Practice Standards Committee: Adult Cardiac Surgery. 2021 The American Association for Thoracic Surgery expert consensus document: Surgical treatment of acute type A aortic dissection. J Thorac Cardiovasc Surg. 2021;162(3):735-758.e2. doi: 10.1016/j.jtcvs.2021.04.053.

22: Drullinsky D, Mehta CK, Scott MB, Crawford E, Markl M, Bonow RO, Mendelson MA, El-Hamamsy I, Malaisrie SC. Four-dimensional magnetic resonance after Ross procedure for unicuspid aortic valve. Circ Cardiovasc Imaging. 2021;14(4):e011500. doi: 10.1161/CIRCIMAGING.120.011500.

23: Bonow RO, O'Gara PT. Reconsidering the Ross procedure. JAMA Cardiol. 2021;6(5):548. doi: 10.1001/jamacardio.2021.0087.

24: Ward A, Malaisrie SC, Andrei AC, Bonow RO, Thomas JD, Puthumana J, Pham DT, Churyla A, Kruse J, McCarthy PM. Fate of moderate aortic regurgitation after cardiac surgery. J Thorac Cardiovasc Surg. 2022;164(6):1784-1792.e1. doi: 10.1016/j.jtcvs.2020.12.114.

25: Son AY, Jarvis K, Markl M, Malaisrie SC. 4D flow MRI after aortic replacement with frozen elephant trunk using thoraflex hybrid graft. J Card Surg. 2021 Apr;36(4):1543-1545. doi: 10.1111/jocs.15427.

26: Mehta CK, Malaisrie SC, Budd AN, Okita Y, Matsuda H, Fleischman F, Ueda Y, Bavaria JE, Moon MR. Triage and management of aortic emergencies during the coronavirus disease 2019 (COVID-19) pandemic: A consensus document supported by the American Association for Thoracic Surgery (AATS) and Asian Society for Cardiovascular and Thoracic Surgery (ASCVTS). J Thorac Cardiovasc Surg. 2020;161(1):48–53. doi: 10.1016/j.jtcvs.2020.06.004.

27: Malaisrie SC, Mehta CK. Updates on indications for TEVAR in type B aortic dissection. Innovations (Phila). 2020;15(6):495-501. doi: 10.1177/1556984520961037.

28: Mehta CK, Bavaria JE. Distal repair after frozen elephant trunk: open or endovascular? Ann Cardiothorac Surg. 2020;9(3):226-227. doi: 10.21037/acs-2020-fet-26.

29: Crawford EE, McCarthy PM, Malaisrie SC, Puthumana JJ, Robinson JD, Markl M, Liu M, Andrei AC, Guzzardi DG, Kruse J, Fedak PWM. Applications of a specialty bicuspid aortic valve program: clinical continuity and translational collaboration. J Clin Med. 2020;9(5):1354. doi: 10.3390/jcm9051354.

30: Johnson EMI, Heller JA, Garcia Vicente F, Sarnari R, Gordon D, McCarthy PM, Barker AJ, Etemadi M, Markl M. Detecting aortic valve-induced abnormal flow with seismocardiography and cardiac MRI. Ann Biomed Eng. 2020;48(6):1779-1792. doi: 10.1007/s10439-020-02491-3.

31: Berhane H, Scott M, Elbaz M, Jarvis K, McCarthy P, Carr J, Malaisrie C, Avery R, Barker A, Robinson JD, Rigsby CK, Markl M. Fully automated 3D aortic segmentation of 4D flow MRI for hemodynamic analysis using deep learning. Magn Reson Med. 2020;84(4):2204-2218. doi: 10.1002/mrm.28257.

32: Scott MB, Huh H, van Ooij P, Chen V, Herrera B, Elbaz M, McCarthy P, Malaisrie SC, Carr J, Fedak PWM, Markl M, Barker AJ. Impact of age, sex, and global function on normal aortic hemodynamics. Magn Reson Med. 2020;84(4):2088-2102. doi: 10.1 002/mrm.28250.

33: Soulat G, McCarthy P, Markl M. 4D dlow with MRI. Annu Rev Biomed Eng. 2020;22:103-126. doi: 10.1146/annurev-bioeng-100219-110055.

34: Bollache E, Knott KD, Jarvis K, Boubertakh R, Dolan RS, Camaioni C, Collins L, Scully P, Rabin S, Treibel T, Carr JC, van Ooij P, Collins JD, Geiger J, Moon JC, Barker AJ, Petersen SE, Markl M. Two-minute k-space and time-accelerated aortic four-dimensional flow MRI: dual-center study of feasibility and impact on velocity and wall shear stress quantification. Radiol Cardiothorac Imaging. 2019;1(2):e180008. doi: 10.1148/ryct.2019180008.

35: Stefek HA, Lin KH, Rigsby CK, Michelena HI, Aouad P, Barker AJ, Robinson JD. Eccentric enlargement of the aortic sinuses in pediatric and adult patients with bicuspid aortic valves: a cardiac MRI study. Pediatr Cardiol. 2020;41(2):350-360. doi: 10.1007/s00246-019-02264-3.

36: Jarvis K, Pruijssen JT, Son AY, Allen BD, Soulat G, Vali A, Barker AJ, Hoel AW, Eskandari MK, Malaisrie SC, Carr JC, Collins JD, Markl M. Parametric hemodynamic 4D flow mri maps for the characterization of chronic thoracic descending aortic dissection. J Magn Reson Imaging. 2020;51(5):1357-1368. doi: 10.1002/jmri.26986.

37: Johnson EMI, Etemadi M, Malaisrie SC, McCarthy PM, Markl M, Barker AJ. Seismocardiography and 4D flow MRI reveal impact of aortic valve replacement on chest acceleration and aortic hemodynamics. J Card Surg. 2020;35(1):232-235. doi: 10.1111/jocs.14289.

38: Allen BD, Aouad PJ, Burris NS, Rahsepar AA, Jarvis KB, Francois CJ, Barker AJ, Malaisrie SC, Carr JC, Collins JD, Markl M. Detection and hemodynamic evaluation of flap fenestrations in type B aortic dissection with 4d flow mri: comparison with conventional MRI and CTA. Radiol Cardiothorac Imaging. 2019;1(1):e180009. doi: 10.1148/ryct.2019180009.

39: Elbaz MSM, Scott MB, Barker AJ, McCarthy P, Malaisrie C, Collins JD, Bonow RO, Carr J, Markl M. Four-dimensional virtual catheter: noninvasive assessment of intra-aortic hemodynamics in bicuspid aortic valve disease. Radiology. 2019;293(3):541-550. doi: 10.1148/radiol.2019190411.

40: Bollache E, Fedak PWM, Markl M, Barker AJ. On the 'cusp' of clinical feasibility: aortic wall shear stress derived non-invasively with 4D flow MRI. J Thorac Dis. 2019;11(7):E96-E97. doi: 10.21037/jtd.2019.06.54.

41: Suwa K, Rahman OA, Bollache E, Rose MJ, Rahsepar AA, Carr JC, Collins JD, Barker AJ, Markl M. Effect of aortic valve disease on 3D hemodynamics in patients with aortic dilation and trileaflet aortic valve morphology. J Magn Reson Imaging. 2020;51(2):481-491. doi: 10.1002/jmri.26804.

42: Rahman O, Scott M, Bollache E, Suwa K, Collins J, Carr J, Fedak P, McCarthy P, Malaisrie C, Barker AJ, Markl M. Interval changes in aortic peak velocity and wall shear stress in patients with bicuspid aortic valve disease. Int J Cardiovasc Imaging. 2019;35(10):1925-1934. doi: 10.1007/s10554-019-01632-7.

43: Ma LE, Markl M, Chow K, Huh H, Forman C, Vali A, Greiser A, Carr J, Schnell S, Barker AJ, Jin N. Aortic 4D flow MRI in 2 minutes using compressed sensing, respiratory controlled adaptive k-space reordering, and inline reconstruction. Magn Reson Med. 2019;81(6):3675-3690. doi: 0.1002/mrm.27684.

44: Garcia J, Barker AJ, Markl M. The role of imaging of flow patterns by 4D flow MRI in aortic stenosis. JACC Cardiovasc Imaging. 2019;12(2):252-266. doi: 10.1016/j.jcmg.2018.10.034.

45: Mehta CK, Malaisrie SC. Commentary: How old is too old for aortic arch surgery? J Thorac Cardiovasc Surg. 2019;158(4):982-983. doi: 10.1016/j.jtcvs.2018.11.114.

46: Szlapka M, Michel E, Ricciardi MJ, Malaisrie SC. Valve-in-valve-prosthesis embolization and aortic dissection: single procedure, double complication. Eur J Cardiothorac Surg. 2019;56(1):204-205. doi: 10.1093/ejcts/ezy424.

47: Mazine A, El-Hamamsy I, Verma S, Peterson MD, Bonow RO, Yacoub MH, David TE, Bhatt DL. Ross procedure in adults for cardiologists and cardiac surgeons: JACC State-of-the-art review. J Am Coll Cardiol. 2018;72(22):2761-2777. doi: 10.1016/j.jacc.2018.08.2200.

48: Ma LE, Vali A, Blanken C, Barker AJ, Malaisrie C, McCarthy P, Collins JD, Carr JC, Schnell S, Markl M. Altered aortic 3-Dimensional hemodynamics in patients with functionally unicuspid aortic valves. Circ Cardiovasc Imaging.2018;11(8):e007915. doi: 10.1161/CIRCIMAGING.118.007915.

49: Jarvis K, Schnell S, Barker AJ, Rose M, Robinson JD, Rigsby CK, Markl M. Caval to pulmonary 3D flow distribution in patients with Fontan circulation and impact of potential 4D flow MRI error sources. Magn Reson Med. 2019;81(2):1205-1218. doi: 10.1002/mrm.27455.

50: Shan Y, Li J, Wang Y, Wu B, Barker AJ, Markl M, Wang C, Wang X, Shu X. Aortic stenosis exacerbates flow aberrations related to the bicuspid aortic valve fusion pattern and the aortopathy phenotype. Eur J Cardiothorac Surg. 2019;55(3):534-542. doi: 10.1093/ejcts/ezy308.

51: Rose MJ, Rigsby CK, Berhane H, Bollache E, Jarvis K, Barker AJ, Schnell S, Allen BD, Robinson JD, Markl M. 4-D flow MRI aortic 3-D hemodynamics and wall shear stress remain stable over short-term follow-up in pediatric and young adult patients with bicuspid aortic valve. Pediatr Radiol. 2019;49(1):57-67. doi: 10.1007/s00247-018-4257-y.

52: Bollache E, Guzzardi DG, Sattari S, Olsen KE, Di Martino ES, Malaisrie SC, van Ooij P, Collins J, Carr J, McCarthy PM, Markl M, Barker AJ, Fedak PWM. Aortic valve-mediated wall shear stress is heterogeneous and predicts regional aortic elastic fiber thinning in bicuspid aortic valve-associated aortopathy. J Thorac Cardiovasc Surg. 2018;156(6):2112-2120.e2. doi: 10.1016/j.jtcvs.2018.05.095.

53: Borger MA, Fedak PWM, Stephens EH, Gleason TG, Girdauskas E, Ikonomidis JS, Khoynezhad A, Siu SC, Verma S, Hope MD, Cameron DE, Hammer DF, Coselli JS, Moon MR, Sundt TM, Barker AJ, Markl M, Della Corte A, Michelena HI, Elefteriades JA. The American Association for Thoracic Surgery consensus guidelines on bicuspid aortic valve-related aortopathy: Full online-only version. J Thorac Cardiovasc Surg. 2018;156(2):e41-e74. doi: 10.1016/j.jtcvs.2018.02.115.

54: Borger MA, Fedak PWM, Stephens EH, Gleason TG, Girdauskas E, Ikonomidis JS, Khoynezhad A, Siu SC, Verma S, Hope MD, Cameron DE, Hammer DF, Coselli JS, Moon MR, Sundt TM, Barker AJ, Markl M, Della Corte A, Michelena HI, Elefteriades JA. The American Association for Thoracic Surgery consensus guidelines on bicuspid aortic valve-related aortopathy: Executive summary. J Thorac Cardiovasc Surg. 2018;156(2):473-480. doi: 10.1016/j.jtcvs.2017.10.161.

55: Barker AJ, Markl M, Fedak PWM. Assessing wall stresses in bicuspid aortic valve-associated aortopathy: Forecasting the perfect storm? J Thorac Cardiovasc Surg. 2018;156(2):471-472. doi: 10.1016/j.jtcvs.2018.03.092.

56: Khoynezhad A, DelaRosa J, Moon MR, Brinkman WT, Thompson RB, Desai ND, Malaisrie SC, Girardi LN, Bavaria JE, Reece TB; PROTECT Investigators. Facilitating hemostasis after proximal aortic surgery: results of the PROTECT trial. Ann Thorac Surg. 2018;105(5):1357-1364. doi: 10.1016/j.athoracsur.2017.12.013.

57: Bollache E, Fedak PWM, van Ooij P, Rahman O, Malaisrie SC, McCarthy PM, Carr JC, Powell A, Collins JD, Markl M, Barker AJ. Perioperative evaluation of regional aortic wall shear stress patterns in patients undergoing aortic valve and/or proximal thoracic aortic replacement. J Thorac Cardiovasc Surg. 2018;155(6):2277-2286.e2. doi: 10.1016/j.jtcvs.2017.11.007.

58: Geiger J, Rahsepar AA, Suwa K, Powell A, Ghasemiesfe A, Barker AJ, Collins JD, Carr JC, Markl M. 4D flow MRI, cardiac function, and T<sub>1</sub> -mapping: Association of valve-mediated changes in aortic hemodynamics with left ventricular remodeling. J Magn Reson Imaging. 2018;48(1):121-131. doi: 10.1002/jmri.25916.

59: Shen X, Schnell S, Barker AJ, Suwa K, Tashakkor L, Jarvis K, Carr JC, Collins JD, Prabhakaran S, Markl M. Voxel-by-voxel 4D flow MRI-based assessment of regional reverse flow in the aorta. J Magn Reson Imaging. 2018;47(5):1276-1286. doi: 10.1002/jmri.25862.

60: Condemi F, Campisi S, Viallon M, Troalen T, Xuexin G, Barker AJ, Markl M, Croisille P, Trabelsi O, Cavinato C, Duprey A, Avril S. Fluid- and biomechanical analysis of ascending thoracic aorta aneurysm with concomitant aortic insufficiency. Ann Biomed Eng. 2017;45(12):2921-2932. doi: 10.1007/s10439-017-1913-6.

61: van Ooij P, Markl M, Collins JD, Carr JC, Rigsby C, Bonow RO, Malaisrie SC, McCarthy PM, Fedak PWM, Barker AJ. Aortic valve stenosis alters expression of regional aortic wall shear stress: new insights from a 4-dimensional flow magnetic resonance imaging study of 571 subjects. J Am Heart Assoc. 2017;6(9):e005959. doi: 10.1161/JAHA.117.005959.

62: Fatehi Hassanabad A, Barker AJ, Guzzardi D, Markl M, Malaisrie C, McCarthy PM, Fedak PWM. Evolution of precision medicine and surgical strategies for bicuspid aortic valve-associated aortopathy. Front Physiol. 2017;8:475. doi: 10.3389/fphys.2017.00475.

63: Garcia J, van der Palen RLF, Bollache E, Jarvis K, Rose MJ, Barker AJ, Collins JD, Carr JC, Robinson J, Rigsby CK, Markl M. Distribution of blood flow velocity in the normal aorta: Effect of age and gender. J Magn Reson Imaging. 2018;47(2):487-498. doi: 10.1002/jmri.25773.

64: Raghav V, Barker AJ, Mangiameli D, Mirabella L, Markl M, Yoganathan AP. Valve mediated hemodynamics and their association with distal ascending aortic diameter in bicuspid aortic valve subjects. J Magn Reson Imaging. 2018;47(1):246-254. doi: 10.1002/jmri.25719.

65: Campo JJ, Yamashita MH, Malaisrie SC. Creating a 90° curve in polyester grafts during thoracic aortic surgery using the pleat technique. J Thorac Cardiovasc Surg. 2017;154(2):414-416. doi: 10.1016/j.jtcvs.2016.12.052.

66: van der Palen RL, Barker AJ, Bollache E, Garcia J, Rose MJ, van Ooij P, Young LT, Roest AA, Markl M, Robinson JD, Rigsby CK. Altered aortic 3D hemodynamics and geometry in pediatric Marfan syndrome patients. J Cardiovasc Magn Reson. 2017;19(1):30. doi: 10.1186/s12968-017-0345-7.

67: Murphy IG, Collins J, Powell A, Markl M, McCarthy P, Malaisrie SC, Carr JC, Barker AJ. Comprehensive 4-stage categorization of bicuspid aortic valve leaflet morphology by cardiac MRI in 386 patients. Int J Cardiovasc Imaging. 2017;33(8):1213-1221. doi: 10.1007/s10554-017-1107-1.

68: Shan Y, Li J, Wang Y, Wu B, Barker AJ, Markl M, Wang C, Wang X, Shu X. Aortic shear stress in patients with bicuspid aortic valve with stenosis and insufficiency. J Thorac Cardiovasc Surg. 2017;153(6):1263-1272.e1. doi: 10.1016/j.jtcvs.2016.12.059.

69: Trinh B, Dubin I, Rahman O, Ferreira Botelho MP, Naro N, Carr JC, Collins JD, Barker AJ. Aortic volumetry at contrast-enhanced magnetic resonance angiography: feasibility as a sensitive method for monitoring bicuspid aortic valve aortopathy. Invest Radiol. 2017;52(4):216-222. doi: 10.1097/RLI.0000000000000332.

70: Jarvis K, Vonder M, Barker AJ, Schnell S, Rose M, Carr J, Robinson JD, Markl M, Rigsby CK. Hemodynamic evaluation in patients with transposition of the great arteries after the arterial switch operation: 4D flow and 2D phase contrast cardiovascular magnetic resonance compared with Doppler echocardiography. J Cardiovasc Magn Reson. 2016;18(1):59. doi: 10.1186/s12968-016-0276-8.

71: Garcia J, Barker AJ, Collins JD, Carr JC, Markl M. Volumetric quantification of absolute local normalized helicity in patients with bicuspid aortic valve and aortic dilatation. Magn Reson Med. 2017;78(2):689-701. doi: 10.1002/mrm.26387.

72: Schnell S, Smith DA, Barker AJ, Entezari P, Honarmand AR, Carr ML, Malaisrie SC, McCarthy PM, Collins J, Carr JC, Markl M. Altered aortic shape in bicuspid aortic valve relatives influences blood flow patterns. Eur Heart J Cardiovasc Imaging. 2016 Nov;17(11):1239-1247. doi: 10.1093/ehjci/jew149.

73: Bollache E, van Ooij P, Powell A, Carr J, Markl M, Barker AJ. Comparison of 4D flow and 2D velocity-encoded phase contrast MRI sequences for the evaluation of aortic hemodynamics. Int J Cardiovasc Imaging. 2016;32(10):1529-41. doi: 10.1007/s10554-016-0938-5.

74: Keller EJ, Malaisrie SC, Kruse J, McCarthy PM, Carr JC, Markl M, Barker AJ, Collins JD. Reduction of aberrant aortic haemodynamics following aortic root replacement with a mechanical valved conduit. Interact Cardiovasc Thorac Surg. 2016;23(3):416-23. doi: 10.1093/icvts/ivw173.

75: Havelka GE, Tomita TM, Malaisrie SC, Ho KJ, Eskandari MK. Two cases of aortic intimal intussusception during endovascular repair of an acute type B dissection. J Endovasc Ther. 2016;23(3):521-8. doi: 10.1177/1526602816644917.

76: Fedak PWM, Barker AJ. Is Concomitant aortopathy unique with bicuspid aortic valve stenosis? J Am Coll Cardiol. 2016;67(15):1797-1799. doi: 10.1016/j.jacc.2016.02.038.

77: Allen BD, Markl M, Barker AJ, van Ooij P, Carr JC, Malaisrie SC, McCarthy P, Bonow RO, Kansal P. Influence of beta-blocker therapy on aortic blood flow in patients with bicuspid aortic valve. Int J Cardiovasc Imaging. 2016;32(4):621-8. doi: 10.1007/s10554-015-0819-3.

78: Fedak PW, Barker AJ, Verma S. Year in review: bicuspid aortopathy. Curr Opin Cardiol. 2016;31(2):132-8. doi: 10.1097/HCO.0000000000000258.

79. Zamor KC, Eskandari MK, Rodriguez HE, Ho KJ, Morasch MD, Hoel AW. Outcomes of thoracic endovascular aortic repair and subclavian revascularization techniques. J Am Coll Surg. 2015;221(1):93-100. doi: 10.1016/j.jamcollsurg.2015.02.028.

80: Taylor AP, Yadlapati A, Andrei AC, Li Z, Clennon C, McCarthy PM, Thomas JD, Malaisrie SC, Stone NJ, Bonow RO, Fedak PW, Puthumana JJ. Statin use and aneurysm risk in patients with bicuspid aortic valve disease. Clin Cardiol. 2016;39(1):41-7. doi: 10.1002/clc.22492

81: van Ooij P, Garcia J, Potters WV, Malaisrie SC, Collins JD, Carr JC, Markl M, Barker AJ. Age-related changes in aortic 3D blood flow velocities and wall shear stress: Implications for the identification of altered hemodynamics in patients with aortic valve disease. J Magn Reson Imaging. 2016;43(5):1239-49. doi: 10.1002/jmri.25081.

82: Schnell S, Entezari P, Mahadewia RJ, Malaisrie SC, McCarthy PM, Collins JD, Carr J, Markl M. Improved semiautomated 4D flow MRI analysis in the aorta in patients with congenital aortic valve anomalies versus tricuspid aortic valves. J Comput Assist Tomogr. 2016;40(1):102-8. doi:10.1097/RCT.0000000000000312.

83: Garcia J, Barker AJ, Murphy I, Jarvis K, Schnell S, Collins JD, Carr JC,Malaisrie SC, Markl M. Four-dimensional flow magnetic resonance imaging-based characterization of aortic morphometry and haemodynamics: impact of age, aortic diameter, and valve morphology. Eur Heart J Cardiovasc Imaging. 2016;17(8):877-84. doi: 10.1093/ehjci/jev228.

84: Guzzardi DG, Barker AJ, van Ooij P, Malaisrie SC, Puthumana JJ, Belke DD, Mewhort HE, Svystonyuk DA, Kang S, Verma S, Collins J, Carr J, Bonow RO, Markl M, Thomas JD, McCarthy PM, Fedak PW. Valve-related hemodynamics mediate human bicuspid aortopathy: insights from wall shear stress mapping. J Am Coll Cardiol. 2015;66(8):892-900. doi: 10.1016/j.jacc.2015.06.1310.

85: Collins JD, Semaan E, Barker A, McCarthy PM, Carr JC, Markl M, Malaisrie SC. Comparison of hemodynamics after aortic root replacement using valve-sparing or bioprosthetic valved conduit. Ann Thorac Surg. 2015;100(5):1556-62. doi: 10.1016/j.athoracsur.2015.04.109.

86: Andrei AC, Yadlapati A, Malaisrie SC, Puthumana JJ, Li Z, Rigolin VH, Mendelson M, Clennon C, Kruse J, Fedak PW, Thomas JD, Higgins JA, Rinewalt D, Bonow RO, McCarthy PM. Comparison of outcomes and presentation in men-versus-women with bicuspid aortic valves undergoing aortic valve replacement. Am J Cardiol. 2015;116(2):250-5. doi: 10.1016/j.amjcard.2015.04.017.

87: Malaisrie SC, Duncan BF, Mehta CK, Badiwala MV, Rinewalt D, Kruse J, Li Z, Andrei AC, McCarthy PM. The addition of hemiarch replacement to aortic root surgery does not affect safety. J Thorac Cardiovasc Surg. 2015;150(1):118-24.e2. doi: 10.1016/j.jtcvs.2015.03.020.

88: Chowdhary V, Rose M, Murtagh G, Schnell S, Barker A, Russell H, Markl M, Carr J. Impact of ascending to descending aortic bypass for aortic coarctation on 3-dimensional hemodynamics. Circulation. 2015;131(11):1036-8. doi: 10.1161/circulationaha.114.014382.

89: Sang SL, Hodges KE, Majewski M, Malaisrie SC. Malformed aortic valve mimicking type A aortic dissection. J Card Surg. 2015;30(5):452. doi: 10.1111/jocs.12534.

90: Allen BD, van Ooij P, Barker AJ, Carr M, Gabbour M, Schnell S, Jarvis KB, Carr JC, Markl M, Rigsby C, Robinson JD. Thoracic aorta 3D hemodynamics in pediatric and young adult patients with bicuspid aortic valve. J Magn Reson Imaging. 2015;42(4):954-63. doi: 10.1002/jmri.24847.

91: Garcia J, Barker AJ, van Ooij P, Schnell S, Puthumana J, Bonow RO, Collins JD, Carr JC, Markl M. Assessment of altered three-dimensional blood characteristics in aortic disease by velocity distribution analysis. Magn Reson Med. 2015;74(3):817-25. doi: 10.1002/mrm.25466

92: van Ooij P, Potters WV, Collins J, Carr M, Carr J, Malaisrie SC, Fedak PW, McCarthy PM, Markl M, Barker AJ. Characterization of abnormal wall shear stress using 4D flow MRI in human bicuspid aortopathy. Ann Biomed Eng. 2015;43(6):1385-97. doi: 10.1007/s10439-014-1092-7.

93: Kent WD, Manjunath A, Malaisrie SC. Frozen elephant trunk repair for descending thoracic aortic dissection in a man with a hostile left pleural cavity. Tex Heart Inst J. 2014;41(3):341-3. doi: 10.14503/THIJ-13-3369.

94: Merritt BA, Turin A, Markl M, Malaisrie SC, McCarthy PM, Carr JC. Association between leaflet fusion pattern and thoracic aorta morphology in patients with bicuspid aortic valve. J Magn Reson Imaging. 2014;40(2):294-300. doi: 10.1002/jmri.24376.

95: Garcia J, Markl M, Schnell S, Allen B, Entezari P, Mahadevia R, Chris Malaisrie S, Pibarot P, Carr J, Barker AJ. Evaluation of aortic stenosis severity using 4D flow jet shear layer detection for the measurement of valve effective orifice area. Magn Reson Imaging. 2014;32(7):891-8. doi: 10.1016/j.mri.2014.04.017.

96: Rinewalt D, McCarthy PM, Malaisrie SC, Fedak PW, Andrei AC, Puthumana JJ, Bonow RO. Effect of aortic aneurysm replacement on outcomes after bicuspid aortic valve surgery: validation of contemporary guidelines. J Thorac Cardiovasc Surg. 2014;148(5):2060-9. doi: 10.1016/j.jtcvs.2014.03.027.

97: van Ooij P, Potters WV, Nederveen AJ, Allen BD, Collins J, Carr J, Malaisrie SC, Markl M, Barker AJ. A methodology to detect abnormal relative wall shear stress on the full surface of the thoracic aorta using four-dimensional flow MRI. Magn Reson Med. 2015;73(3):1216-27. doi: 10.1002/mrm.25224.

98: Mahadevia R, Barker AJ, Schnell S, Entezari P, Kansal P, Fedak PW, Malaisrie SC, McCarthy P, Collins J, Carr J, Markl M. Bicuspid aortic cusp fusion morphology alters aortic three-dimensional outflow patterns, wall shear stress, and expression of aortopathy. Circulation. 2014;129(6):673-82. doi: 10.1161/circulationaha.113.003026.

99: Galizia MS, Barker A, Liao Y, Collins J, Carr J, McDermott MM, Markl M. Wall morphology, blood flow and wall shear stress: MR findings in patients with peripheral artery disease. Eur Radiol. 2014;24(4):850-6. doi: 10.1007/s00330-013-3081-x.

100: Semaan E, Markl M, Malaisrie SC, Barker A, Allen B, McCarthy P, Carr JC, Collins JD. Haemodynamic outcome at four-dimensional flow magnetic resonance imaging following valve-sparing aortic root replacement with tricuspid and bicuspid valve morphology. Eur J Cardiothorac Surg. 2014;45(5):818-25. doi: 10.1093/ejcts/ezt526.

101: Entezari P, Schnell S, Mahadevia R, Malaisrie C, McCarthy P, Mendelson M, Collins J, Carr JC, Markl M, Barker AJ. From unicuspid to quadricuspid: influence of aortic valve morphology on aortic three-dimensional hemodynamics. J Magn Reson Imaging. 2014;40(6):1342-6. doi: 10.1002/jmri.24498.

102: Allen BD, Barker AJ, Kansal P, Collins JD, Carr JC, Malaisrie SC, Markl M. Impact of aneurysm repair on thoracic aorta hemodynamics. Circulation. 2013;128(17):e341-3. doi: 10.1161/circulationaha.112.000850.

103: Barker AJ, van Ooij P, Bandi K, Garcia J, Albaghdadi M, McCarthy P, Bonow RO, Carr J, Collins J, Malaisrie SC, Markl M. Viscous energy loss in the presence of abnormal aortic flow. Magn Reson Med. 2014;72(3):620-8. doi: 10.1002/mrm.24962.

104: Barker AJ, Robinson JD, Markl M. Bicuspid aortic valve phenotype and aortopathy: nomenclature and role of aortic hemodynamics. JACC Cardiovasc Imaging. 2013;6(8):921. doi: 10.1016/j.jcmg.2013.03.006.

105: Allen BD, Barker AJ, Carr JC, Silverberg RA, Markl M. Time-resolved three-dimensional phase contrast MRI evaluation of bicuspid aortic valve and coarctation of the aorta. Eur Heart J Cardiovasc Imaging. 2013;14(4):399. doi: 10.1093/ehjci/jes225.

106: Barker AJ, Markl M. The role of hemodynamics in bicuspid aortic valve disease. Eur J Cardiothorac Surg. 2011;39(6):805-6. doi: 10.1016/j.ejcts.2011.01.006.

*Bolding of author’s name indicates Northwestern Medicine staff and/or Northwestern University Feinberg School of Medicine faculty.