Treatments

Bladder Cancer Treatments

The treatment for bladder cancer is dependent on the grade and stage of the cancer. Northwestern Medicine physicians use current state of the art guidelines to give you the highest quality of care. Many of our physicians participate in national committees to help guide standard of care procedures.

Surgery

Surgery for bladder cancer is performed by a Northwestern Medicine oncology specialist. Surgical treatment options for bladder cancer include:

  • Transurethral removal: The mainstay of treatment for non-muscle-invasive bladder cancer is surgical removal. This may include standard white-light or blue-light cystoscopy.
  • Bladder removal: For patients with muscle-invasive (T2+) cancer, bladder removal provides the best chance for cure. Northwestern Medicine urologists use both open and minimally invasive surgery for surgical treatment of bladder cancer.

Intravesical Therapies

  • BCG treatment: The main treatment for high-grade non-muscle-invasive bladder cancer is treatment with BCG (Bacillus Calmette-Guerin) into the bladder. These treatments increase the immune response and are the best way to decrease the recurrence of bladder cancer.
  • Chemotherapy: Chemotherapy for BCG refractory bladder cancer is used to treat cancers that are not responsive to BCG treatment. Northwestern Medicine clinicians have experience in treating these cancers with the use of novel chemotherapies.
  • Trials in immunotherapy: Clinicians and investigators at Northwestern Medicine have extensive experience with clinical trials to treat patients with new agents and immunomodulators to treat non-muscle invasive bladder cancer.

Chemotherapy

For patients with muscle-invasive (T2) or greater cancers, a medical oncologist is a critical part of their Northwestern Medicine bladder cancer team. Chemotherapy drugs may be administered, either intravenously or orally, to treat cancerous cells that have spread outside the bladder.

Radiation Therapy

Patients with muscle-invasive bladder cancer may elect to preserve their bladder. Radiotherapy is delivered in combination with surgery (endoscopic resection), chemotherapy and radiation. Your multi-disciplinary specialty team will discuss if this option is right for you.

Novel Therapies

We offer state-of-the-art therapy, such as immunotherapy and cancer-targeted therapies in clinical trials.

Palliative Medicine

Side effects from cancer treatment can impact your quality of life and your body’s ability to respond to treatment. Northwestern Medicine is home to a diverse team of palliative medicine specialists who work with your oncologist to help relieve your pain and manage your symptoms. The palliative medicine specialists:

  • Treat pain and other physical symptoms of cancer, such as fatigue, nausea, trouble sleeping, poor appetite, breathing difficulties and weight loss.
  • Treat emotional symptoms, such as depression and anxiety.
  • Improve your body’s ability to tolerate cancer treatments.
  • Help you better understand tests, procedures and options.
  • Guide you and those who care for you to helpful outside resources.

From your initial diagnosis throughout your care, the palliative medicine team can help you remain stronger in your fight against cancer and feel better, every step of the way.