What causes transverse myelitis?

In most cases, transverse myelitis occurs due to an issue that is causing inflammation in the spinal cord. This may include:

  • Systemic autoimmune diseases such as lupus and Sjogren’s disease
  • Neuromyelitis optica
  • Myelin oligodendrocyte glycoprotein associated demyelination (MOGAD)
  • Sarcoidosis
  • Multiple sclerosis
  • Lyme disease
  • Syphilis
  • Viral, bacterial and fungal infections

In some cases, the cause of transverse myelitis is unknown.